Corneal Wound Healing After Keratorefractive Procedures

Bowman’s layer is composed of 22nm heterotypical type I collagen fibrils, which are randomly orientated (mean direction 45o to the corneal surface). Immediately beneath Bowman’s membrane, the cornea is arranged such that there are about 300 lamellae centrally and 500 lamellae peripherally. Each is composed of uniformly paralleldirected, 25nm heterotypical type I collagen fibrils with flattened keratocytes present between some adjacent lamellae. In the anterior third of the stroma, lamellae are orientated in oblique directions to the corneal surface; they branch extensively and are interwoven with other lamellar layers both anteroposteriorly and horizontally.